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Rabeprazole 40mg, Domperidone 30mg SR


Composition:  Rabeprazole 40mg, Domperidone 30mg SR

Rabeprazole: It is a proton pump inhibitor that inhibits gastric acid secretion and is taken orally in the form of its sodium salt.

Domperidone:- It is antiemetic medicine that increases the movements or contractions of stomach and bowel.

Mode of Action:-

Rabeprazole:- Rabeprazole belongs to a class of anti secretory compound that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid Secretion by inhibiting the gastric H + K + ATPase at the secretory surface of the gastric parietal.

Domperidone:- It is specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release and is used as antiemetic.

Indications and usage:-


  • It is used to treat excessive stomach pain
  • Used in adults to promote healing of duodenal ulcers
  • Use to treat symptoms of Gasteroesophageal reflux disease (GERD)


  • It is used to prevent stomach problems such as nausea and vomiting associated with certain medications used to treat Parkinson’s disease
  • It improves symptoms of nausea and vomiting, bloating, and feeling of fullness.

Side effects:-


  • Nausea and vomiting
  • Weight gain or loss
  • Headache
  • Yellow eyes
  • Increased thirst
  • Dark urine
  • Cough


  • Nausea
  • Abdominal cramps
  • Rash and itching
  • Dry mouth
  • Diarrhea
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