best anti cold Suspension available in pharma pcd

best anti cold Suspension available in pharma pcd 

PARLEO QR

Composition : Phenylephrine HCL, Chlorpheniramine Maleate, paracetamol Suspension

Phenylephrine: It is a decongestant that shrinks blood vessels.It is used to treat nasal and sinus congestion.

Chlorpheniramine Maleate: It is a bronchodilator used to treat asthma.

 Paracetamol: Paracetamol is a pain reliever and fever reducer.

Suspension: It is a cephalosporin type antibiotic used to treat a wide variety of bacterial infections.

Mode Of Action :-

Phenylephrine: It is a post-synaptic alpha-adrenergic receptor agonist that cause vasoconstriction, increases systolic/diastolic pressure and stroke output.

Chlorpheniramine: It acts primarily as a potent H1 antihistamine. It is specifically a potent inverse agonist of the histamine H1 receptor. The drug is also commonly described as possessing weak anticholinergic activity by acting as an antagonist of the muscarinic acetylcholine receptors.

Paracetamol: It is a weak inhibitor of the synthesis of prostaglandins (PGs).However, the in vivo effects of paracetamol are similar to that selective cyclooxygenase-2 (COX-2) inhibitors. Paracetamol is thought to relieve pain by reducing the production of prostaglandins in the brain and spinal cord.

Suspension: It works by stopping the growth of bacteria.

Indications and usage:-

Phenylephrine:

• It is used to treat sinus congestion or congestion of tubes that drain fluid from your inner ears.
• It is used to treat nasal congestion

Chlorpheniramine:

• It used to relieve symptoms of allergy
• Hay fever
• Common cold
• Sneezing
• Watery eyes

Paracetamol:

• It is used for the relief pain such as headache, toothache.
• It is used to reduce fever and cold.
• It is used for influenza, joint pain and periods pain.

Suspension:

It is used to treat wide variety of bacterial infections:

• Skin infection
• Bone infection
• Genitourinary tract infections

Side effects:-

Phenylephrine: Common  side effect:

• Discomfort
• Chest pain
• Dizziness
• Fainting
• Headache
• Nausea and vomiting
• Sweating

Chlorpheniramine Maleate

• Stomach upset
• Blurred vision
• Dry mouth
• Dizziness
• Constipation

Paracetamol: 

• Nausea and Vomiting
• Stomach pain
• Loss of appetite
• Dark urine
• Jaundice (yellowing of the skin or eyes)

 Suspension: 

• Stomach upset
• Nausea
• Headache
• Diarrhea
• Dizziness