Ceftriaxone 1mg, Sulbactam 500mg

injections Ceftriaxone 1mg + Sulbactam 500mg

IMICEF-S 1.5

Composition: Ceftriaxone 1mg + Sulbactam 500mg

Ceftriaxone: It is an antibiotic used for the treatment of a number of bacterial infections.

Sulbactam :Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria.

Mode Of Action:-

Ceftriaxone: Ceftriaxone inhibits bacterial cell wall synthesis by binding to transpeptidases, also called transamidases, which are penicillin-binding proteins (PBPs) that catalyze the cross-linking of the peptidoglycan polymers forming the bacterial cell wall.

Sulbactam: Sulbactam acts as β-lactamase inhibitors, to increase the antibacterial activity of Cefoperazone against β-lactamase producing organisms.

Indications and usage:-

Ceftriaxone: The drug used to treat conditions such as:

• Respiratory tract infections
• Skin infections
• Urinary tract infections
• Pelvic inflammatory disease
• Bone and joint infection
• Meningitis

Sulbactam:

• Infections of female reproductive organ
• Skin infections
• Abdominal infection

Side effects:

Ceftriaxone:

• Nausea and vomiting
• Change in the amount of urine
• Abdominal pain
• Sign of kidney problem
• Tiredness
• Allergic reaction
• Dizziness

Sulbactam:

• Vaginal itching
• Mild diarrhea
• Swollen, black tongue
• Mild skin rash